The Online Home For Dog Breeders

Featuring Dog Breeders, Puppies For Sale, and Dog Breeds

Bookmark and Share


Support Dog
Health Testing
For Healthier Puppies
QualityDogs.com is your home for puppies, dog breeders, and dog health information. If you are a dog lover who is interested in learning about dog breeds, researching dog breeders, or even finding a puppy to add to your home, you are in the right place. To find current puppies for sale by site members, or to search our entire dog breeders list by breed, click on the menu bar to the left. While you are here, don't forget to check our out informative Dog Articles section, and post your own pictures and comments on our Breed Profile pages!
Are you a responsible dog breeder? Click here to find out how to join QualityDogs.com and appear on the site!
Featured Puppy Announcements
Latest Message Board Topics

Pyruvate Kinase Deficiency

Pyruvate Kinase Deficiency, or PK Deficiency, is the lack of a critical red blood cell enzyme (pyruvate kinase), which regulates the final step in the conversion of glucose to energy. As a result, red blood cells are not able to metabolize the energy required for the cells to function normally, which leads to a change in the cell membranes, a buildup of sodium ions inside the cell, a resulting swelling of the cell (as water molecules follow the buildup of sodium), and an eventual lysing (bursting) of the cell. Furthermore, there is a shortened life span of red blood cells as the abnormal cells are destroyed by the spleen and liver. To make matters worse, PK deficiency, through the changes described above, can shift the normal process by which hemoglobin stores and releases oxygen to body tissues. The end result of these changes produces "hemolytic anemia," which is a reduction in red blood cells and tissue oxygenation due to the rupture of abnormal red blood cells.

PK Deficiency Inheritance
Pyruvate Kinase Deficiency is an autosomal recessive trait, which means that, for a dog to have PK Deficiency, both parents must be either affected dogs themselves or carriers. Affected dogs will have two copies of the bad gene, while carriers will only have one copy and will not clinically show symptoms, although studies have shown that carriers do have a reduction in normal red blood cell enzyme activity.
-Read the whole article
Read on! Check out:   Dog Health   |   Dog Nutrition   |   Training   |   Grooming   |   more articles
Recent Visitor Comments
Glen of Imaal Terrier
Recently we rescued of Glen of Imaal from our local SPCA. She is 4 yrs old and is a very focused little girl. A mind of her own, not real affectionate, but very loyal at the same time. She has trained me well.

Akita
I've owned 2 male Akitas. They've both been very healthy, low maintenance, friendly to humans, have lived with other pets but are NOT good with other males. Don't require a great deal of exercise.. A walk twice a day is plenty. Mine chew ice cubes after a walk. Neither of them showed any real interest in chewing anything else, but this has proven to keep their teeth and gums healthy and it's kind of funny, too. Can't sing their praises enough. Wonderful family membe

Coton de Tulear
My frenid Joan in My frenid Joan in Toronto was featured on Dogs With Jobs in Canada about 10 years ago. She had´╗┐ a standard poodle named Morgan as her narcolepsy service dog, and to our knowledge he was the first in the world. Joan now has Shaba as her service dog. Because the collapses in narcolepsy are actually paralysis (cataplexy) rather than sleep, Shaba's job is to drag her to a safe place when she's going to collapse, and stand over her and protect her while she's down. Was this

Post your comments in our Breed Profiles
Latest Blog Entries

Featured Breed -

Brussels Griffon

The Brussels Griffon At a Glance
Recognized By AKC
Country of Origin Belgium
Life Expectancy 12 - 15 yrs
Height Range 7 - 8 in
Weight Range 8 - 10 lbs
Colors Red, beige, black & tan, or black. No white hairs or markings
Trainability Can be good with a skilled and patient trainer; they tend to be stubborn
With Children Good with older children; can be nervous around overly active younger children
With Animals Very good; does well with other dogs and cats
Climate Intolerant of cold weather
Indoor/Outdoor Indoor with some outdoor time preferred; can do well in apartment/condo
Exercise Reqd Moderate to high; walks and play time are sufficient
Grooming Reqd Proper coat requires regular brushing and hand stripping by a knowledgeable groomer.
Brussels Griffon Information
The Brussels Griffon is a breed of toy dog named for the griffin, a mythological animal, which it is said to resemble. The Brussels griffon seems to have descended from a dog used by 17th-century Belgian peasants to rid their stables of rats. The ancestry of the modern breed includes the Affenpinscher, the Smooth-Coated Pug, and the Ruby Spaniel.

Conformation

Brussels Griffons have distinctive short, upturned faces, large, round heads, short noses, and unusually large and prominent black eyes. The male Griffon from 7 to 12 pounds. The female is slightly larger.

Disposition

The Brussels Griffon is intelligent, alert, sensitive, and full of self-importance with an almost human expression.

They are inside pets, good with other pets and children of all ages.

There are two types of coats, rough and smooth. They come in colors of Beige, Black, Black and Beige and Red.

Courtesy of Kelly Crawford, KMC-Kennels.
Click to find:   Brussels Griffon Puppies For Sale   |   Brussels Griffon Breeders   |   Brussels Griffon Information

Dog Question of the Week

Some answers to last week's question:
Does your dog LIKE going to the vet?
This Week's Question:
What is the funniest thing your dog has ever done?
Like? My dog Scout LOVES going to the vet! She knows that is where she gets a lot of attention and treats. She is a big girl so she has to go to the back to get weighed and I can always hear other employees fawning over her. One time when we had to get shots as well I heard the tech telling
Jessica from Hawley, PA, USA
She's not sure... she gets excited to go for a ride, but then when we start in the door at the vet's office she freezes. Once we're inside, though, she's in heaven.
Paula from Waukeegan, WI, USA
Dog Question of the Week
What is the funniest thing your dog has ever done?
Your first name
Your city
State/province
Country
 
By submitting, you grant QualityDogs.com the right to publish your submission (including your name/location if supplied) on this or affiliated websites, and to edit your submission for content, spelling, and/or grammar.
Google+