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Following are health screenings often performed on breeding Mastiff adults; choosing a puppy from a breeder who tests parents for health can help avoid future health problems in your puppy:
Cardiac Evaluation - OFA
CERF Screening (Canine Eye Research Foundation)
Elbow Displasia (OFA, by X-Ray)
Hip Dysplasia (OFA or PennHIP)
Progressing Retinal Atrophy (genetic test)
Thyroid Function Test (blood test)